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Ellagic Acid

Rejuvenation Therapeutics

RTX-DS2500-030

  • A potent antioxidant.*
  • Provides cognitive function and immunity support.*

Suitable for Vegans. Gluten Free. No artificial fillers, No Rice.

30 Vegan Capsules (250mg).

   FREE SHIPPING ON ORDERS OVER $25!

Suggested Use: Take 1 capsule daily, or as directed by your qualified health care professional.

Warning: Consult a health care professional prior to use if you are pregnant or nursing, taking any medications, or have any medical conditions. Keep out of reach of children.

Store in a cool, dry place.

Other Ingredients: Ellagic Acid from Promegranate (Punica granatum), Organic Potato Starch, Hypromellose (Capsule).


What is Ellagic Acid?

Ellagic acid is a phenolic phytochemical, chemically characterized as a natural dimeric derivative of gallic acid. The occurrence of free ellagic acid in dietary foodstuffs is uncommon; it is usually conjugated with a glycoside moiety, such as glucose, or forms part of the polymeric ellagitannins.[1] It is found in raspberries, strawberries, pomegranates, pecans, walnut and other food plants.


What are the Benefits of Ellagic Acid Supplements?

  • Pomegranate extract contains ellagitannin, a polyphenolic compound, which acts as a potent antioxidant. A clinical study was done with 64 overweight individuals with increased waist line. The subjects consumed pomegranate ellagitannin-enriched polyphenol extract capsules. The study demonstrates that the pomegranate ellagitannin-enriched polyphenol extract capsules are totally safe for consumption and enhance antioxidant activities in humans.[2]
  • Ellagic acid acts as an anti-inflammatory agent. It exhibited a potent anti- inflammatory effect against carrageenan-induced inflammation. The mechanisms of ellagic acid induced protection were due to reduction of NO, MDA, IL-1β, TNF-α, COX-2 and NF-κB expression and induction of GSH and IL-10 production.[3]
  • Ellagic acid acts as memory restorative agent in the treatment of dementia and prevents cognitive and LTP deficiency [4]. Ellagic acid has shown improvement in the motor impairments and neuroprotective effect in Parkinson model.[5]

Why Take Ellagic Acid Supplements?

Ellagic acid supplements serve as a convenient option for anyone looking to improve the immunity and get rid of oxidative stress. Our Ellagic acid supplement contains 250 mg of standardized ellagic acid from pomegranate extract (90%).


What are the Side Effects of Ellagic Acid Ingestion?

No significant side effects are reported for ellagic acid supplements.


References

  1. Larrosa, M., Tomás-Barberán, F. A., & Espín, J. C. (2006). The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway. The Journal of nutritional biochemistry, 17(9), 611-625.
  2. Heber D, Seeram NP, Wyatt H, Henning SM, Zhang Y, Ogden LG, Dreher M, Hill JO. Safety and antioxidant activity of a pomegranate ellagitannin-enriched polyphenol dietary supplement in overweight individuals with increased waist size. Journal of Agricultural and Food Chemistry. 2007 Oct 30;55(24):10050-4.
  3. El-Shitany, N. A., El-Bastawissy, E. A., & El-desoky, K. (2014). Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism. International immunopharmacology, 19(2), 290-299.
  4. Farbood Y, Sarkaki A, Dolatshahi M, Mansouri SM, Khodadadi A. Ellagic Acid Protects the Brain Against 6-Hydroxydopamine Induced Neuroinflammation in a Rat Model of Parkinson’s.
  5. Sarkaki A, Farbood Y, Dolatshahi M, Mansouri SM, Khodadadi A. Neuroprotective Effects of Ellagic Acid in a Rat Model of Parkinson's Disease. Acta Medica Iranica. 2016 Sep 17;54(8):494-502.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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